Madeline Sayet is a member of the Mohegan Tribe in Connecticut, where she was raised on a combination of traditional Mohegan stories and Shakespeare. Both of which have influenced her work as a stage director of new plays, classics, and opera. 

For her work she has been named a Forbes 30 Under 30 in Hollywood & Entertainment, a NCAIED Native American 40 Under 40, a TED Fellow,  MIT Media Lab Director's Fellow,, and a recipient of the White House Champion of Change Award from President Obama. She is the Executive Director of the Yale Indigenous Performing Arts Program (YIPAP). Within her field she has also been acknowledged as a 2019 Drama League Director in Residence, a member of the 2016 National Directors Fellowship Cohort, a Finalist for the TCG Alan Schneider Directing Award, and is currently a member of Long Wharf Theatre's inaugural artistic ensemble. Her directorial work has been described by critics as effervescent, enchanting, magical, insightful, and fearless. 

She received her BFA in Drama from Tisch School of the Arts, where she studied under the Atlantic Theatre Company. She has a MA in Arts Politics & Post-Colonial Theory from NYU's Gallatin School of Individualized Study, and a MA in Shakespeare & Creativity (with Distinction) from The Shakespeare Institute (Stratford Upon Avon, UK). 

After finishing her studies at NYU, she received directing mentorship through a Van Lier Directing Fellowship at Second Stage Theatre,  and social entrepreneurship training as part of the first cohort of National Arts Strategies' Creative Community Fellows (where she now serves as a mentor), before going on to develop a national and international artistic career.

She has served on panels for the NEA, Mellon Foundation, Jerome Many Voices Fellowship, ART NY grants, as well as the Artistic Council for the O'Neill Playwrights Conference. Her writing has been published by TCG (Theatre Communications Group), Howlround Theatre Commons, University of Nebraska Press, and No Passport Press.

Her directing work has been seen at the Long Wharf Theatre, Perseverance Theatre (Alaska), Denver Center for the Performing Arts, Connecticut Repertory Theatre, Delaware Shakespeare Festival, South Dakota Shakespeare Festival, Orlando Shakespeare Festival, The Krannert Center (Illinois), Theatresquared (Arkansas), Penobscot Theatre (Maine), the Public Theater (NY), HERE Arts Center (NY), 59e59 Theaters (NY), Ars Nova (NY), Lark Play Development Center (NY), the Glimmerglass Festival (NY), as well as in Iceland and the UK.